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:: Volume 9, Issue 2 (Summer 2007) ::
J Mil Med 2007, 9(2): 139-146 Back to browse issues page
Occurrance of Emphysema and Accuracy of Pulmonary Function Test (PFT), ‎Comparing with Chest High Resolution Computed Tomography (HRCT), in ‎Smokers with History of Exposure to Toxic Fumes
Ghanei M.‎, Alikhani Sh. *, Mirmohammad S. M. M‎., Adibi I‎., Ramezani T.‎, Aslani J.‎
, alikhani7821@yahoo.com
Abstract:   (21946 Views)

Objective. To study the occurrence of emphysema and accuracy of Pulmonary Function Test ‎‎(PFT), comparing with chest High Resolution Computed Tomography (HRCT), in smokers with ‎history of exposure to toxic fumes (Sulfur Mustard SM). ‎

Material and Methods. This was a cross sectional study (2003 - 2004) on 20 symptomatic ‎smokers with mild SM exposure (Group I) and 20 smokers without SM exposure (Group II). ‎PFT and CHEST HRCT were performed for all patients to detect emphysema. Sensitivity, ‎specificity, and positive and negative predictive values were calculated for PFT. ‎

Results. PFT did not diagnose emphysema in group I while CHEST HRCT diagnosed five ‎patients (sensitivity= 0). Group II developed emphysema (11 of 20, 55%) more frequently than ‎group I (5 of 20, 20%, p<0.05). No α1-antitrypsin deficiency was found in all 70 individuals. ‎ Conclusions. Smokers with an additional risk factor, such as exposure to toxic fumes, develop ‎emphysema at younger ages while they have normal PFT. CHEST HRCT should be regarded as ‎a useful tool in the early diagnosis of emphysema in such cases.‎

Keywords: Emphysema, High Resolution Computed Tomography, Pulmonary Function Test, ‎Smoking, Sulfur Mustard, toxic fumes
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Type of Study: Orginal Research | Subject: military medcine
Received: 2008/02/25 | Published: 2007/07/15
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Ghanei M.‎, Alikhani Sh., Mirmohammad S. M. M‎., Adibi I‎., Ramezani T.‎, Aslani J.‎. Occurrance of Emphysema and Accuracy of Pulmonary Function Test (PFT), ‎Comparing with Chest High Resolution Computed Tomography (HRCT), in ‎Smokers with History of Exposure to Toxic Fumes. J Mil Med. 2007; 9 (2) :139-146
URL: http://militarymedj.ir/article-1-494-en.html


Volume 9, Issue 2 (Summer 2007) Back to browse issues page
مجله طب‌نظامی Journal Mil Med
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